杨炜 教授 个人简历 杨炜,博士,校聘教授,山东省海外高层次青年人才。2007年获佳木斯大学学士学位,2013年获南开大学博士学位,2013-2017年在中国科学院生物物理研究所任助理研究员,2018-2025年在德国弗莱堡大学进行博士后研究工作,2026年入职山东农业大学食品科学与工程学院。在Nature Communications、Protein Cell和Plant Physiology等国际主流学术期刊上发表论文10余篇。主持山东省海外高层次青年人才项目和国家自然科学基金青年项目各1项。 研究方向聚焦于细胞衰老与肿瘤发生的分子机制,致力于解析其关键调控网络,并探索食品来源活性成分在延缓衰老及肿瘤干预中的作用机制。通过整合分子与细胞生物学及多组学技术手段,深化对相关生物学过程的认识,推动天然活性分子在健康老龄化与疾病防控中的应用。 欢迎对细胞生物学、衰老机制、肿瘤研究及天然活性物质感兴趣的同学加入。 发表论文(*第一作者;✉通讯作者) 1. Yang W*, Cong S*, Li R, Schwarz J, Schulze T, Gevelhoff R, Chen X, Ullrich S, Falkenstein K, Ott D, Eixmann P, Trentino A, Thien A, Heidmann T, Schulze E, Warscheid B, Baumeister R✉, and Qi W✉. Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition. Nat Commun. 16(1):6327.(2025). 2. Yang W* and Zhang N✉. Preventing transposons from jumping by transposon-derived small RNAs. Plant Physiol. 199(1):kiaf389. (2025). 3. Zhang X*, Yang W*, Wang X, Zhang X, Tian H, Deng H, Zhang L, and Gao G✉. Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-β activation. Protein Cell. 9(9): 799-807. (2018). 4. Yang W*, Tan J*, Liu R, Cui X, Ma Q, Geng Y, and Qiao W✉. Interferon-gamma upregulates expression of IFP35 gene in HeLa cells via interferon regulatory factor-1. PLoS One 7(12): e50932. (2012). 5. Yan F*, Yang W, Wang X, and Gao G✉. TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication. J Virol. 96(17): e0091922. (2022). 6. Qi W*✉, Gromoff E, Xu F, Zhao Q, Yang W, Pfeifer D, Maier W, Long L, and Baumeister R. The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans. Nat Commun.12(1):1262. (2021). 7. Luo X*, Yang W, and Gao G✉. SUN1 Regulates HIV-1 Nuclear Import in a Manner Dependent on the Interaction between the Viral Capsid and Cellular Cyclophilin A. J Virol. 92(13): e00229-18. (2018). 8. Wang M*, Yang W, Chen Y, Wang J, Tan J✉, and Qiao W✉. Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression. Retrovirology. 15(1):65. (2018). 9. Hu X*, Yang W, Liu R, Geng Y, Qiao W, and Tan J✉. N-Myc interactor inhibits prototype foamy virus by sequestering viral Tas protein in the cytoplasm. J Virol. 88(12): 7036-44. (2014). 10. Liu R*, Tan J*, Lin Y, Jia R, Yang W, Liang C, Geng Y, and Qiao W✉. HIV-1 Vpr activates both canonical and noncanonical NF-kappaB pathway by enhancing the phosphorylation of IKKalpha/beta. Virol. 439(1): 47-56. (2013). 11. Huo L*, Li D, Sun X, Shi X, Karna P, Yang W, Liu M, Qiao W, Aneja R, and Zhou J✉. Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6. J Biol Chem. 286(11): 9280-6. (2011). 12. Tan J*, Hao P*, Jia R, Yang W, Liu R, Wang J, Xi Z, Geng Y, and Qiao W✉. Identification and functional characterization of BTas transactivator as a DNA-binding protein. Virol. 405(2): 408-13. (2010). 联系方式 邮件:wei-yang@126.com |