刘慧

讲师

个人简介：

刘慧，工学博士，园艺学博士后，讲师，硕士生导师。担任《Food Safety and Health》国际期刊编委，《eFood》国际期刊青年编委。目前主要从事食品营养健康领域的教学与科研工作，主讲食品营养与安全学、食品质量与安全综合实验两门课程。主持国家自然科学基金青年项目、山东省自然科学基金青年项目等科研项目3项。在Critical Reviews in Food Science and Nutrition、、Free Radical Biology and Medicine等学术期刊发表SCI论文20余篇，授权发明专利2项。

主要研究方向：

1. 食品营养与功能成分调控机体代谢、调节肠道菌群、干预代谢性疾病等机制研究。

2. 天然活性成分的交互作用及健康调控机制。

代表性科研项目：

1. 国家自然科学基金青年基金，No. 3240162053，30万，主持

2. 山东省自然科学基金青年项目，No. ZR2021QC194，12万，主持

代表性科研论文：

1. Liu, H., Guan, H., He F. T., Song Y., Li, F., Sun-Waterhouse, D. X., Li, D. P., Therapeutic actions of tea phenolic compounds against oxidative stress and inflammation as central mediators in the development and progression of health problems: A review focusing on microRNA regulation. Critical Reviews in Food Science and Nutrition, 2024, 64 (23), 8414-8444.

2. Liu, H., Guan, H., Tan, X. T., Jiang, Y., Li, F., Sun-Waterhouse, D. X., Li, D. P., Enhanced alleviation of insulin resistance via the IRS-1/Akt/FOXO1pathway by combining quercetin and EGCG and involving miR-27a-3p and miR-96–5p. Free Radical Biology and Medicine, 2022, 181, 105-117.

3. . Liu, H., Wang, L., Li, F., Jiang, Y., Guan, H., Wang, D., Sun-Waterhouse, D. X., Wu, M. Y. Li, D.P, The synergistic protection of EGCG and quercetin against streptozotocin (STZ)-induced NIT-1 pancreatic βcell damage via upregulation of BCL-2 expression by miR-16-5p. Journal of Nutritional Biochemistry, 2021, 96, 108748.

4. Liu, H., Zhu, X. F., Jiang, Y., Sun‐Waterhouse, D. X., Huang, Q. R., Li, F., Li, D. P., Physicochemical and emulsifying properties of whey protein isolate (WPI)‐polydextrose conjugates prepared via Maillard reaction. International Journal of Food Science & Technology, 2021,56 (8), 3784–3794.

5. Liu, H., Jiang, Y., Guan, H., Li, F., Sun-Waterhouse, D. X., Chen, Y.L., Li, D.P., Enhancing the antioxidative effects of foods containing rutin and α‐amino acids via the Maillard reaction: A model study focusing on rutin‐lysine system. Journal of Food Biochemistry, 2020,1-12.

6. Guan, H., Zhang, W. Y., Liu, H., Jiang, Y., Li, F., Wang, D., Liu, Y., He, F. T., Wu, M. Y., Ivan Neil Waterhouse, G., Sun-Waterhouse D. X., Li D. P., Simultaneous binding of quercetin and catechin to FOXO3 enhances IKKα transcription inhibition and suppression of oxidative stress-induced acute alcoholic liver injury in rats. Journal of Advanced Research, 2025, 67, 71-92.

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